EXHIBIT 21.1


SUBSIDIARIES OF PROPHASE LABS, INC.

State or other
Jurisdiction of
Ownership
Subsidiaries
Incorporation
Percentage
Nebula Genomics Holdings, Inc.
Delaware
100
%
Nebula Genomics, Inc.
Delaware
100
%
ProPhase Biopharma, Inc.
Delaware
100
%
ProPhase Diagnostics, Inc.
Delaware
100
%
ProPhase Diagnostics NY, Inc.
Delaware
100
%
ProPhase Diagnostics UT, Inc.
Delaware
100
%
ProPhase Global Healthcare, Inc.
Delaware
100
%
ProPhase Digital Media, Inc.
Delaware
100
%
Quigley Pharma Inc.
Delaware
100
%
TK Supplements, Inc.
Delaware
100
%
ProPhase Billing Services, Inc.
Delaware
100
%
DNA Complete, Inc.
Delaware
100
%

The above subsidiaries are included in the consolidated financial statements for the year ended December 31, 2025.