ProPhase Labs, Inc. to Release First Quarter Results on Monday, May 17

DOYLESTOWN, Pennsylvania – May 14, 2010. ProPhase Labs (Nasdaq: PRPH) announced today that financial results for the fiscal 2010 first quarter, ended March 31, 2010, will be released just after the market closes on Monday, May 17, 2010. An earnings conference call will be held the following morning on Tuesday May 18th at 11:00 AM. ProPhase Chairman and CEO, Ted Karkus, and COO/CFO Robert Cuddihy will provide a Company overview including a review of activities and first quarter results. There will be a question and answer session following initial remarks.

The conference call will be webcast live at http://event.meetingstream.com/r.htm?e=201053&s=1&k=FB759E9EF564864738AF09E742BEC903 at 11:00 AM (EST) on Tuesday May 18, 2010.

Participants wishing to ask questions may access the live call by dialing (877) 217-6026 conference ID# 76110570. A replay of the conference call will be available for 90 days on the Company web site at www.prophaselabs.com.

ProPhase Labs is a diversified natural health medical science company. It is a leading marketer and manufacturer of the Cold-EEZE® family of lozenges and sugar free tablets clinically proven to significantly reduce the severity and duration of the common cold. Cold-EEZE customers include leading national wholesalers and distributors, as well as independent and chain food, drug and mass merchandise stores and pharmacies. ProPhase Labs has several wholly owned subsidiaries including a manufacturing unit, which consists of an FDA approved facility to manufacture Cold-EEZE lozenges and fulfill other contract manufacturing opportunities, and a Pharma division, which conducts research in order to develop and commercialize a pipeline of patented botanical and naturally derived potential prescription drugs. ProPhase also owns 50% of Phusion Laboratories LLC (“Phusion”). Phusion licenses a revolutionary proprietary technology that has the potential to improve the delivery and/or efficacy of many active ingredients or compounds. The joint venture will formulate and test products to exploit market opportunities within ProPhase’s robust OTC distribution channels.

For more information visit us at www.ProPhaseLabs.com.

Wendi@lexicommgroup.com

Lindsey@lexicommgroup.com

Chairman of the Board, CEO