Management Team

Ted Karkus, CEO and Chairman of ProPhase Labs, drives the company’s diverse and synergistic businesses with his successful track record in biomedical and health companies. He transformed ID Biomedical’s strategy and valuation from $25 million to $1.4 billion sale to GlaxoSmithKline.  As CEO of ProPhase Labs, he restructured the go-to-market strategy for the flagship product Cold-EEZE, turned around and significantly grew revenues, ultimately selling it for $50 million to Mylan.

ProPhase Labs is a fast-growing biotech, genomics and diagnostics company due to its commitment to growth, innovation, and execution excellence outlined in Ted’s high growth roadmap. He pivoted into industry leading CLIA labs, and then further diversified by acquiring genomics leader Nebula Genomics.  Constantly innovating, Ted then created ProPhase BioPharma to deliver antivirals, cancer tests and therapeutic cancer compounds. The new acquisitions and legacy businesses work to drive synergistic growth with multi-billion-dollar potential.

He holds a BS in Psychology from Tufts University with Magna Cum Laude Honors and an MBA in Finance from Columbia University School of Business with Beta Gamma Sigma Honors.

Steven M. Plumb, CPA is a seasoned senior executive and financial manager experienced in operations, finance and marketing. He has Big 4 CPA experience, a background in IT, gaming, biotech, oil and gas, real estate, medical and utility companies. Mr. Plumb has served as the chief financial officer of numerous public companies over the course of his career as a fractional CFO. From April 2024 to August 2025, Mr. Plumb served as the chief financial officer of Driveitaway Holdings, Inc. (OTC:DWAY). From September 2023 to November 2024, Mr. Plumb served as the chief financial officer of A Game Beverages, Inc. From August 2022 to June 2024, Mr. Plumb served as the chief financial officer of Endexx Corp. (OTCBB:EDXC). From October 2020 to July 2023, Mr. Plumb served as the chief financial officer of Gaming Technologies, Inc. (OTCBB:GMGT). From January 2020 to March 2023, Mr. Plumb served as the chief financial officer of Directview Holdings, Inc. (OTCBB:DIRV). From January 2019 to October 2021, Mr. Plumb served as the chief financial officer of Artella Solutions, Inc. Since 2001, he has served as the owner and president of Clear Financial Solutions, a consulting firm that provides interim CFO services to small public companies. In this capacity he has prepared SEC filings, managed investor relations, raised capital, conducted mergers and acquisition activities, developed successful offering memorandum, registration statements and investor presentations. Mr. Plumb is a former auditor with PriceWaterhouseCoopers and KPMG. Mr. Plumb has a Bachelor of Business Administration degree from the University of Texas at Austin, Austin, Texas.

Jason drove explosive revenue growth at ProPhase Diagnostics, leading multiple areas including sales, business development, logistics operations, and account management. He oversaw the development of two CLIA-certified labs, generating approximately $200 million in revenues since 2021 and manages account managers and customer service reps who offer 24/7 service to exceed customer expectations. Jason now heads up business development for the rapid build-out of ProPhase’s Nebula Genomics business.

With a background in sales and development at top real estate firms, Jason is a graduate of the University of Maryland.

Kevin holds both a Master’s and undergraduate degree from the University of Washington, with a background that bridges technology, design, art and artificial intelligence. He worked as a Product Manager at Google, where he led cross-functional teams to build scalable, user-centric solutions for the Android ecosystem. He is also a co-founder of Nebula Genomics, which he built from the ground up – transforming it into a cutting-edge platform at the intersection of genomics and technology.

Lance is an accomplished finance leader experienced in all areas of finance and accounting. Lance has over 17 years of experience in working with large brands, both public and private, of varying industries and sizes.

Prior to ProPhase Labs, Lance served in finance leadership roles at multiple large brand companies including Colgate-Palmolive, Casper Sleep, Newmark and Forest Laboratories, where he was responsible for all accounting matters including financial reporting, general accounting, and related internal controls functions. He began his career with five years in public accounting with Marcum LLP. Lance earned a BBA in accounting from Hofstra University. He is a certified public accountant and is a member of the American Institute of Certified Public Accountants.

Along with being a co-founder at Nebula Genomics, Dr. George Church is also Professor of Genetics at Harvard Medical School and Director of PersonalGenomes.org. His 1984 Harvard Ph.D. included the first methods for direct genome sequencing, molecular multiplexing & barcoding. This led to the first genome sequence (pathogen, Helicobacter pylori) in 1994. His innovations have contributed to nearly all “next-generation” DNA sequencing methods and companies (CGI-BGI, Life, Illumina, Nanopore). His honors include election to NAS & NAE & Franklin Bower Laureate for Achievement in Science. He has co-authored 590 papers, 155 patent publications and  one book (Regenesis).

Joe Abdo is a molecular oncology scientist with 18+ years of experience in cancer diagnostics, translational research, and biotech business development. He has held leadership roles in public and private life science companies, focusing on early cancer detection, immunotherapy response prediction, and clinical utility studies. He has authored 35+ peer-reviewed publications, which have been cited 900+ times in the fields of molecular oncology, proteomics, and precision medicine. As Vice President of Clinical Diagnostics at Oxford BioDynamics, he leads clinical strategy and real-world evidence programs for 3D genomic testing platforms. A brain cancer survivor, Joe channels his personal experience into advancing patient-centered innovations. He also lectures at Georgetown University Medical Center, teaching ‘Entrepreneurial Biotechnology’ and ‘Core Methods in Biotechnology,’ and has received Georgetown’s Outstanding Mentor Award (2022 & 2025) and Creighton’s Academic Achievement Award (2018).

James Renwick McCullough is the founder of Renalytix Plc, serving as Chief Executive Officer & Director since 2018. Mr. McCullough is also the founder of Paige. Ai, Inc. Current jobs include Chairman at BalletNext, Inc., Director at The Bonnie J. Addario Lung Cancer Foundation, Director at Kantaro Biosciences LLC, Director at Renalytix AI, Inc., Non-Executive Director at Verici Dx Plc since 2020, and Director at Go2 Foundation For Lung Cancer. Former jobs include Chief Executive Officer at Exosome Diagnostics, Inc. from 2008 to 2014, Director at Quentra Networks, Inc., Director at Ausam Biotechnologies, Inc., Director at TAVEC Pharmaceuticals, Independent Non-Executive Director at LungLife AI, Inc. from 2019 to 2024, and Managing Partner at Renwick Capital LLC from 2014 to 2021. Education includes an undergraduate degree from Boston University and an MBA from Columbia Business School.